The owners aimed to create a cool place to be, harkening back to the ’60s and ’70s when people came to Sardinia to hide and not “be seen.” They also love paintings and were compelled to fill the spaces with art. Cozy yet refined, the home has rustic sensibilities like exposed wood beams and raw edge wooden counters in the bathroom, balanced by white space.

This exceptional property looks like it belongs in a Bond movie. Built into the side of a mountain with spectacular views overlooking the town of Lucca, it is a masterpiece of design. With the marble of the rock face incorporated into the interior design, a remarkable retractable roof, and an infinity pool that's as sculptural as the works of art inside the house, this villa for rent in Lucca designed by celebrated architect Michel Boucquillon is one for the bucket list.

Working in collaboration with interior designer and editor of Openhouse magazine, Andrew Trotter, the owners of this vacation home rental in Florence have transformed this 16th-century palazzo into a live/work destination with four individual apartments for travelers, an exhibition space, and an artist in residency program that encourages creative expression and development.

Facing the Duomo and just a short stroll from the Uffizzi Gallery, this vacation home rental in Florence is housed in an elegant palazzo in the heart of the birthplace of the Renaissance.

Halfway between Rome and Florence, in the verdant heart of Etruscan Italy, organic winemakers and contemporary art collectors have transformed a 16th-century estate into a luxurious villa of discreet elegance.

This vacation home rental in Venice is where two distinct worlds harmoniously coexist. Outside, the historic grandeur and romance of the city is eternal, but inside, this apartment is a serene inner sanctum of modern Venetian design.

Created as a luxurious space where guests can truly embrace the present, Trullo Mo’ is a combination of Puglia’s cone-topped trullo structures with several additional independent stone buildings.

A sleek, architect-created villa immersed in a centuries’ old olive grove, this luxury retreat combines the best of contemporary design with the leisurely styling of a breezy country estate.

Taking its cue from the the dazzling white town of Ostuni nearby, this luxury villa for rent in Puglia is in harmony with history's footsteps throughout this region.

The turquoise gemstone swimming pool dropped deeply into the ancient courtyard of this historical home gives the residence its modern name, which translates to Sweet Courtyard. Inspired by the riads of Morocco, the outdoor space at this venerable townhouse.

Discovered in a state of semi-abandonment, this 19th-century neo-classical villa for rent in Italy was brought back to its original beauty following its purchase from the local priest.

Located at the mid-point on the western shores, this villa for rent on Lake Como is settled just below the imposing 14th-century castle that rises protectively over the historic fisherman's village of Santa Maria Rezzonico.